GHK-Cu is a naturally occurring human copper complex that down-regulates inflammatory cytokines while stimulating dermal fibroblasts to synthesize new structural collagen.
1. GHK-Cu Dermal Remodeling Mechanisms
- Pro-Collagen Activation: Increases pro-collagen synthesis by up to 70% compared to baseline, outperforming pure retinoic acid in clinical skin elasticity metrics.
- MMP Regulation: Balances Matrix Metalloproteinases (MMPs) to remove damaged cross-linked collagen fibrils and replace them with smooth extracellular matrix.
- Wound Repair Signaling: Chemoattractant properties recruit capillary endothelial cells to enhance micro-circulation in aged tissue.
